Pain Hub T-Shirt

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the expert services that will be provided in the hub and the distinct value that the hub will provide to academic users, industry, and other users Chronic pain is pain that lasts more than 3 months or longer than expected for healing after surgery, injury or a condition. The cause may also be unknown. It is sometimes called 'persistent pain'. It can be a difficult to treat and balancing treatment options is vital. be designed with capacity to evolve and respond to changing needs and opportunities, bring in additional funding and grow in ambition, and incorporate plans for sustainability of the investment, including through grants, industry investment and service provision It is also a debilitating feature of long-term conditions including arthritis, cancer, diabetes and dementia.

Guided by leading experts in pain research in partnership with the NHS, APDP consortia, people with lived experience of chronic pain and industry, the hub will: answer why people with the same visceral disease can have completely different pain experiences, including flares evidence that the applicants provide an existing physical environment of cross-sector collaboration, with strong relationships with multiple key stakeholder groups and academic consortium members to support research and innovation The study receives core funding from the Medical Research Council, the Wellcome Trustand the University of Bristol. Guided by leading experts in pain research in partnership with the NHS, APDP consortia, people with lived experience of chronic pain and industry, Alleviate will:The ADVANTAGE consortium aims to improve how we treat people with visceral diseases, such as endometriosis, Crohn’s disease and Ulcerative Colitis, and Polycystic Kidney Disease, focusing on their pain rather than just their underlying disease. that the hub will deliver a national service that will be financially sustainable in the long-term.

One of our Patient Insight Partners (PIP) provided the analogy: “You have to put books in the library to enhance knowledge.” The proposed use of innovative approaches to data discovery, standardisation, curation and cleaning, along with automation and a scalable secure infrastructure will create a powerful resource, that will be informed by what matters to people living with chronic pain. an overview of the hub including its vision, goals, key partnerships and interfaces and expected outputs The hashtag "#painhub" is also considerably popular on TikTok, with videos under it holding over 1 billion collective views as of May 2021. Typical content under the hashtag similarly denotes feelings of sadness and pain, as well as ironic depictions of it (popular examples shown below). A key question is understanding why some people are severely impacted by NeuP whilst others with a similar pattern of nerve damage are not. Hence, we will identify the personal characteristics (such as age, gender and ethnicity), environmental/social and clinical factors which determine NeuP risk. We will identify and validate novel genetic risk factors for NeuP.

Multidisciplinary consortia

The purpose of the hub is not to perform original research itself, but to underpin research activities supported through other routes. The funding available to applicants will create ‘data as infrastructure’ through the creation of new data and services that improves access to and quality of data and increases the UK’s future research and innovation capability. Timeline for hub delivery Milestone one: hub established (within three months of becoming a hub) harness opportunities to work across the HDR UK Hub network and link to or complement relevant existing investments, nationally and internationally delivery feasibility and risk management, describing how the delivery milestones laid out in the above section will be met, supported by an overall project plan (Gantt Chart – separate attachment) and a discussion of the risks with mitigating actions. Describe the project management process that will provide assurance that the delivery milestones and goals will be achieved

Our work will be divided into various taskforces, each led by an internationally recognised expert clinician or scientist. All research will be enriched by input from patient and patient support organisations from start to finish. Development of a robust UK-wide health data infrastructure to enable long-term impact and persistence.Maximum one side of A4, including a project plan and risk register with mitigating actions. Data management plan Uncover the biological, psychological, and sociological mechanisms which lead to long-term pain; this will include those that are shared between different types of pain, as well as those that are specific to individual diagnoses. Alleviate will collaborate with the APDP consortia (and other groups) to provide a shared platform and data resource. the data sets to be included within the hub, describing the data sets that will be brought together under the APDP initiative and linked to the HDR UK Alliance over the course of the award and include the data custodians, modes and sizes of datasets (number of records, populations covered), the current quality of the data (coverage, completeness, validity, timeliness and accuracy) and the environment in which they are currently stored (process and governance for access) Talking to somebody who cares about you can be really helpful, and sometimes it can even help you feel better.

Milestone three: impact, sustainability and scalability (within two and a half years of becoming a hub) The Pain Research Data Hub will be funded as a part of the UKRI/Versus Arthritis Advanced Pain Discovery Platform, however it is expected to align with the overall vision of Health Data Research UK and to become part of its wider network. This involves aligning with the principles of participation and contributing to the Alliance and the Gateway. This approach builds on the Digital Innovation Hub scheme funded by MRC through the Industrial Strategy Challenge Fund. Funding is available for the development of one hub over three years. We’ll cover 67% of the full economic costs. Dr Neha Issar-Brown, Director of Research at Versus Arthritis, explained: "We are delighted to be supporting Professor Keogh and colleagues to deliver this consortium as part of the ground-breaking Advanced Pain Discovery Platform (APDP). evidence that the quality of the data sets has been improved (curated) and that the curated data is discoverable through the Gatewayexperience as a data processor for several health boards, Scottish Government, and many UK and international research cohorts