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In patients with ischaemic heart disease, treatment with a beta-adrenergic antagonist should be discontinued gradually, i.e. over 1-2 weeks. If necessary replacement therapy should be initiated at the same time, to prevent exacerbation of angina pectoris. For people with circulation problems: This drug can worsen peripheral vascular disease. Talk to your doctor before using this drug if you have a history of circulation problems.

Data in patients with hepatic insufficiency or impaired liver function are limited. Therefore the use of Nebilet in these patients is contra-indicated. Class III antiarrhythmic drugs (Amiodarone): effect on atrio-ventricular conduction time may be potentiated.

Pregnancy & Breastfeeding use

Note that nebivolol is also indicated for hypertension, but has a different dosing regimen for this indication. If you have been told by your doctor to take ½ (half) tablet daily, please refer to the instructions below on how to break Nebivolol 2.5mg and Nebivolol 5mg scored tablets into equal doses. Beside them lay the leftovers of lives cut short: family photographs, school diplomas, Ethiopian flags. Breathlessness such as in asthma, due to sudden cramps in the muscles around the airways. Tightening of the chest, difficulty in breathing or wheezing (bronchospasm) For people with an overactive thyroid gland: This drug may mask the signs and symptoms of an overactive thyroid gland (hyperthyroidism), such as a fast heart rate. If this drug is stopped suddenly, your symptoms of hyperthyroidism may get much worse. You may need urgent medical attention. Tell your doctor if you have any thyroid problems before starting this medication.

For people with breathing problems: This drug can make breathing more difficult for you. Talk to your doctor before using nebivolol if you have any breathing problems such as asthma or chronic obstructive pulmonary disease (COPD). When clonidine is stopped, rebound high blood pressure typically occurs. This means your blood pressure can get high again. This can be much worse if nebivolol is not stopped several days before you stop taking clonidine. Sildenafil The treatment of stable chronic heart failure has to be initiated with a gradual uptitration of dosage until the optimal individual maintenance dose is reached. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

For people with severe kidney disease: The recommended starting dosage for people with severe kidney disease is 2.5 mg once per day. Your doctor will increase your dosage slowly if needed. This drug hasn’t been studied in people on dialysis. If you’re on dialysis, your doctor will monitor you more closely. For women who are breastfeeding: It isn’t known if nebivolol passes into breast milk. If it does, there’s a possibility for serious side effects in children who breastfeed from mothers taking this drug. These side effects include a very slow heart rate. Because of these risks, you should not take nebivolol while breastfeeding. Talk to your doctor if you’re pregnant or planning to become pregnant. Managing high blood pressure during pregnancy is important. However, nebivolol should only be used during pregnancy if the potential benefit justifies the potential risk to your pregnancy. If you take nebivolol and sildenafil (Viagra) together, the amount of sildenafil in your body may decrease. This can lead to decreased effects of sildenafil. In India, nebivolol is available as Nebula (Zydus Healthcare Ltd), Nebizok (Eris life-sciences), Nebicip (Cipla ltd), Nebilong (Micro Labs), Nebistar (Lupin ltd), Nebicard (Torrent), Nubeta ( Abbott Healthcare Pvt Ltd – India), and Nodon (Cadila Pharmaceuticals).

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking nebivolol it is important that your doctor knows:Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p.462. ISBN 9783527607495. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia. Nebilet Cholesterol interaction His troops surrounded the building and killed those who did not surrender, he said during an interview in Mekelle. Reuters could not independently confirm his version of events. Seleme VB, Marques GL, Mendes AE, Rotta I, Pereira M, Júnior EL, da Cunha CL (March 2021). "Nebivolol for the Treatment of Essential Systemic Arterial Hypertension: A Systematic Review and Meta-Analysis". American Journal of Cardiovascular Drugs. 21 (2): 165–180. doi: 10.1007/s40256-020-00422-0. PMID 32710438. S2CID 220732879.